when you see the "wanted" icon next to his name, offer him to clubs (don't specify any particular one) for a price you find reasonable. If the guy doesn't want to part with your team, modify his transfer status to transfer listed, available on loan and not needed by the club. Then send him to the reserves team. The combination of all 4 will piss him off and make him want to move away.
If you don't see the wanted icon, just offer him to clubs the same way, but asking for a lower price. 1 or 2 clubs may respoond.
A player will become wanted if his potential is high, if the guy attracts major clubs you may not want to sell him as he may develop into a real jewel in a few seasons.
I however think you can succeed with any team, no matter how bad the playesr are. What you need is a good training schedule and good coaches, along with an effective game tactic. I would try 4-1-2-1-2 or 4-1-2-2-1. Don't expect immediate results, the first season is just to get them used to you and your new approach, in the second you will start getting some noticeable results and in the 3rd one you'll start shining. One more thing, do your best not to lose your main players, no matter how much other clubs are offering for them. A good way to prevent losing them is to offer new contracts to players in the last year of contract. Give them the maximum 5 years deal to keep them safe in your pocket.
good luck mate, if you have any questions, do post them. | 
